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Regulation of mTORC1 Signaling by pH

BACKGROUND: Acidification of the cytoplasm and the extracellular environment is associated with many physiological and pathological conditions, such as intense exercise, hypoxia and tumourigenesis. Acidification affects important cellular functions including protein synthesis, growth, and proliferat...

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Detalles Bibliográficos
Autores principales: Balgi, Aruna D., Diering, Graham H., Donohue, Elizabeth, Lam, Karen K. Y., Fonseca, Bruno D., Zimmerman, Carla, Numata, Masayuki, Roberge, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126813/
https://www.ncbi.nlm.nih.gov/pubmed/21738705
http://dx.doi.org/10.1371/journal.pone.0021549