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M-CSF Potently Augments RANKL-Induced Resorption Activation in Mature Human Osteoclasts

Macrophage-CSF (M-CSF) is critical for osteoclast (OC) differentiation and is reported to enhance mature OC survival and motility. However, its role in the regulation of bone resorption, the main function of OCs, has not been well characterised. To address this we analysed short-term cultures of ful...

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Detalles Bibliográficos
Autores principales: Hodge, Jason M., Collier, Fiona M., Pavlos, Nathan J., Kirkland, Mark A., Nicholson, Geoffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126821/
https://www.ncbi.nlm.nih.gov/pubmed/21738673
http://dx.doi.org/10.1371/journal.pone.0021462