The In Vivo Role of the RP-Mdm2-p53 Pathway in Signaling Oncogenic Stress Induced by pRb Inactivation and Ras Overexpression

The Mdm2-p53 tumor suppression pathway plays a vital role in regulating cellular homeostasis by integrating a variety of stressors and eliciting effects on cell growth and proliferation. Recent studies have demonstrated an in vivo signaling pathway mediated by ribosomal protein (RP)-Mdm2 interaction...

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Detalles Bibliográficos
Autores principales: Pan, Wenqi, Issaq, Sameer, Zhang, Yanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126829/
https://www.ncbi.nlm.nih.gov/pubmed/21747916
http://dx.doi.org/10.1371/journal.pone.0021625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126829/
https://www.ncbi.nlm.nih.gov/pubmed/21747916
http://dx.doi.org/10.1371/journal.pone.0021625

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