BDNF Facilitates L-LTP Maintenance in the Absence of Protein Synthesis through PKMζ

Late-phase long term potentiation (L-LTP) is thought to be the cellular basis for long-term memory (LTM). While LTM as well as L-LTP is known to depend on transcription and translation, it is unclear why brain-derived neurotrophic factor (BDNF) could sustain L-LTP when protein synthesis is inhibited...

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Detalles Bibliográficos
Autores principales: Mei, Fan, Nagappan, Guhan, Ke, Yang, Sacktor, Todd C., Lu, Bai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126837/
https://www.ncbi.nlm.nih.gov/pubmed/21747912
http://dx.doi.org/10.1371/journal.pone.0021568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126837/
https://www.ncbi.nlm.nih.gov/pubmed/21747912
http://dx.doi.org/10.1371/journal.pone.0021568

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