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Memory B Cells and CD8+ Lymphocytes Do Not Control Seasonal Influenza A Virus Replication after Homologous Re-Challenge of Rhesus Macaques

This study sought to define the role of memory lymphocytes in the protection from homologous influenza A virus re-challenge in rhesus macaques. Depleting monoclonal antibodies (mAb) were administered to the animals prior to their second experimental inoculation with a human seasonal influenza A viru...

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Detalles Bibliográficos
Autores principales: Carroll, Timothy D., Matzinger, Shannon R., Fritts, Linda, McChesney, Michael B., Miller, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126839/
https://www.ncbi.nlm.nih.gov/pubmed/21747924
http://dx.doi.org/10.1371/journal.pone.0021756