Tenascin-C Enhances Pancreatic Cancer Cell Growth and Motility and Affects Cell Adhesion through Activation of the Integrin Pathway

BACKGROUND: Pancreatic cancer (PDAC) is characterized by an abundant fibrous tissue rich in Tenascin-C (TNC), a large ECM glycoprotein mainly synthesized by pancreatic stellate cells (PSCs). In human pancreatic tissues, TNC expression increases in the progression from low-grade precursor lesions to...

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Detalles Bibliográficos
Autores principales: Paron, Igor, Berchtold, Sonja, Vörös, Julia, Shamarla, Madhavi, Erkan, Mert, Höfler, Heinz, Esposito, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126842/
https://www.ncbi.nlm.nih.gov/pubmed/21747918
http://dx.doi.org/10.1371/journal.pone.0021684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126842/
https://www.ncbi.nlm.nih.gov/pubmed/21747918
http://dx.doi.org/10.1371/journal.pone.0021684

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