VapC Toxins from Mycobacterium tuberculosis Are Ribonucleases that Differentially Inhibit Growth and Are Neutralized by Cognate VapB Antitoxins

The chromosome of Mycobacterium tuberculosis (Mtb) encodes forty seven toxin-antitoxin modules belonging to the VapBC family. The role of these modules in the physiology of Mtb and the function(s) served by their expansion are unknown. We investigated ten vapBC modules from Mtb and the single vapBC...

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Detalles Bibliográficos
Autores principales: Ahidjo, Bintou Ahmadou, Kuhnert, Diane, McKenzie, Joanna L., Machowski, Edith E., Gordhan, Bhavna G., Arcus, Vickery, Abrahams, Garth L., Mizrahi, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126847/
https://www.ncbi.nlm.nih.gov/pubmed/21738782
http://dx.doi.org/10.1371/journal.pone.0021738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126847/
https://www.ncbi.nlm.nih.gov/pubmed/21738782
http://dx.doi.org/10.1371/journal.pone.0021738

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