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VapC Toxins from Mycobacterium tuberculosis Are Ribonucleases that Differentially Inhibit Growth and Are Neutralized by Cognate VapB Antitoxins
The chromosome of Mycobacterium tuberculosis (Mtb) encodes forty seven toxin-antitoxin modules belonging to the VapBC family. The role of these modules in the physiology of Mtb and the function(s) served by their expansion are unknown. We investigated ten vapBC modules from Mtb and the single vapBC...
Autores principales: | Ahidjo, Bintou Ahmadou, Kuhnert, Diane, McKenzie, Joanna L., Machowski, Edith E., Gordhan, Bhavna G., Arcus, Vickery, Abrahams, Garth L., Mizrahi, Valerie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126847/ https://www.ncbi.nlm.nih.gov/pubmed/21738782 http://dx.doi.org/10.1371/journal.pone.0021738 |
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