The human Rgr oncogene is overexpressed in T cell malignancies and induces transformation by acting as a GEF for Ras and Ral

The Ras superfamily of GTPases is involved in the modification of many cellular processes including cellular motility, proliferation and differentiation. Our laboratory has previously identified the RalGDS related (Rgr) oncogene in a DMBA-induced rabbit squamous cell carcinoma and its human ortholog...

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Detalles Bibliográficos
Autores principales: Osei-Sarfo, Kwame, Martello, Laura, Ibrahim, Sherif, Pellicer, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126870/
https://www.ncbi.nlm.nih.gov/pubmed/21441953
http://dx.doi.org/10.1038/onc.2011.93

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126870/
https://www.ncbi.nlm.nih.gov/pubmed/21441953
http://dx.doi.org/10.1038/onc.2011.93

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