A novel role for c-Jun N-terminal kinase and phosphoinositide 3-kinase in the liver X receptor-mediated induction of macrophage gene expression

Liver X receptors (LXRs) are ligand-dependent transcription factors that are activated by metabolites of cholesterol, oxysterols, and a number of synthetic agonists. LXRs play potent anti-atherogenic roles in part by stimulating the efflux of cholesterol from macrophage foam cells. The LXR-induced e...

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Detalles Bibliográficos
Autores principales: Huwait, Etimad A., Greenow, Kirsty R., Singh, Nishi N., Ramji, Dipak P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126994/
https://www.ncbi.nlm.nih.gov/pubmed/21070853
http://dx.doi.org/10.1016/j.cellsig.2010.11.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126994/
https://www.ncbi.nlm.nih.gov/pubmed/21070853
http://dx.doi.org/10.1016/j.cellsig.2010.11.002

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