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Global Transcriptomic Profiling Using Small Volumes of Whole Blood: A Cost-Effective Method for Translational Genomic Biomarker Identification in Small Animals

Blood is an ideal tissue for the identification of novel genomic biomarkers for toxicity or efficacy. However, using blood for transcriptomic profiling presents significant technical challenges due to the transcriptomic changes induced by ex vivo handling and the interference of highly abundant glob...

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Detalles Bibliográficos
Autores principales: Fricano, Meagan M., Ditewig, Amy C., Jung, Paul M., Liguori, Michael J., Blomme, Eric A. G., Yang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127131/
https://www.ncbi.nlm.nih.gov/pubmed/21731455
http://dx.doi.org/10.3390/ijms12042502