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Global Transcriptomic Profiling Using Small Volumes of Whole Blood: A Cost-Effective Method for Translational Genomic Biomarker Identification in Small Animals
Blood is an ideal tissue for the identification of novel genomic biomarkers for toxicity or efficacy. However, using blood for transcriptomic profiling presents significant technical challenges due to the transcriptomic changes induced by ex vivo handling and the interference of highly abundant glob...
Autores principales: | Fricano, Meagan M., Ditewig, Amy C., Jung, Paul M., Liguori, Michael J., Blomme, Eric A. G., Yang, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127131/ https://www.ncbi.nlm.nih.gov/pubmed/21731455 http://dx.doi.org/10.3390/ijms12042502 |
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