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The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate maintains bone mass, while the PPAR gamma agonist pioglitazone exaggerates bone loss, in ovariectomized rats

BACKGROUND: Activation of peroxisome proliferator-activated receptor (PPAR)gamma is associated with bone loss and increased fracture risk, while PPARalpha activation seems to have positive skeletal effects. To further explore these effects we have examined the effect of the PPARalpha agonists fenofi...

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Detalles Bibliográficos
Autores principales: Stunes, Astrid K, Westbroek, Irene, Gustafsson, Björn I, Fossmark, Reidar, Waarsing, Jan H, Eriksen, Erik F, Petzold, Christiane, Reseland, Janne E, Syversen, Unni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127763/
https://www.ncbi.nlm.nih.gov/pubmed/21615901
http://dx.doi.org/10.1186/1472-6823-11-11