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Computational Investigation of the Changing Patterns of Subtype Specific NMDA Receptor Activation during Physiological Glutamatergic Neurotransmission

NMDA receptors (NMDARs) are the major mediator of the postsynaptic response during synaptic neurotransmission. The diversity of roles for NMDARs in influencing synaptic plasticity and neuronal survival is often linked to selective activation of multiple NMDAR subtypes (NR1/NR2A-NMDARs, NR1/NR2B-NMDA...

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Detalles Bibliográficos
Autores principales: Singh, Pallab, Hockenberry, Adam J., Tiruvadi, Vineet R., Meaney, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127809/
https://www.ncbi.nlm.nih.gov/pubmed/21738464
http://dx.doi.org/10.1371/journal.pcbi.1002106