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Differential Producibility Analysis (DPA) of Transcriptomic Data with Metabolic Networks: Deconstructing the Metabolic Response of M. tuberculosis

A general paucity of knowledge about the metabolic state of Mycobacterium tuberculosis within the host environment is a major factor impeding development of novel drugs against tuberculosis. Current experimental methods do not allow direct determination of the global metabolic state of a bacterial p...

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Detalles Bibliográficos
Autores principales: Bonde, Bhushan K., Beste, Dany J. V., Laing, Emma, Kierzek, Andrzej M., McFadden, Johnjoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127818/
https://www.ncbi.nlm.nih.gov/pubmed/21738454
http://dx.doi.org/10.1371/journal.pcbi.1002060