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Differential Producibility Analysis (DPA) of Transcriptomic Data with Metabolic Networks: Deconstructing the Metabolic Response of M. tuberculosis
A general paucity of knowledge about the metabolic state of Mycobacterium tuberculosis within the host environment is a major factor impeding development of novel drugs against tuberculosis. Current experimental methods do not allow direct determination of the global metabolic state of a bacterial p...
Autores principales: | Bonde, Bhushan K., Beste, Dany J. V., Laing, Emma, Kierzek, Andrzej M., McFadden, Johnjoe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127818/ https://www.ncbi.nlm.nih.gov/pubmed/21738454 http://dx.doi.org/10.1371/journal.pcbi.1002060 |
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