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Characterization of a synthetic bacterial self-destruction device for programmed cell death and for recombinant proteins release

BACKGROUND: Bacterial cell lysis is a widely studied mechanism that can be achieved through the intracellular expression of phage native lytic proteins. This mechanism can be exploited for programmed cell death and for gentle cell disruption to release recombinant proteins when in vivo secretion is...

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Detalles Bibliográficos
Autores principales: Pasotti, Lorenzo, Zucca, Susanna, Lupotto, Manuel, Cusella De Angelis, Maria Gabriella, Magni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127821/
https://www.ncbi.nlm.nih.gov/pubmed/21645422
http://dx.doi.org/10.1186/1754-1611-5-8