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Sphingosine-1-phosphate promotes the differentiation of human umbilical cord mesenchymal stem cells into cardiomyocytes under the designated culturing conditions

BACKGROUND: It is of growing interest to develop novel approaches to initiate differentiation of mesenchymal stem cells (MSCs) into cardiomyocytes. The purpose of this investigation was to determine if Sphingosine-1-phosphate (S1P), a native circulating bioactive lipid metabolite, plays a role in di...

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Detalles Bibliográficos
Autores principales: Zhao, Zhenqiang, Chen, Zhibin, Zhao, Xiubo, Pan, Fang, Cai, Meihua, Wang, Tan, Zhang, Henggui, Lu, Jian R, Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127825/
https://www.ncbi.nlm.nih.gov/pubmed/21645412
http://dx.doi.org/10.1186/1423-0127-18-37