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Infection by agnoprotein-negative mutants of polyomavirus JC and SV40 results in the release of virions that are mostly deficient in DNA content

BACKGROUND: Human polyomavirus JC (JCV) is the etiologic agent of a brain disease, known as progressive multifocal leukoencephalopathy (PML). The JCV genome encodes a small multifunctional phospho-protein, agnoprotein, from the late coding region of the virus, whose regulatory functions in viral rep...

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Detalles Bibliográficos
Autores principales: Sariyer, Ilker K, Saribas, Abdullah S, White, Martyn K, Safak, Mahmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127838/
https://www.ncbi.nlm.nih.gov/pubmed/21609431
http://dx.doi.org/10.1186/1743-422X-8-255