X Chromosome Inactivation and Differentiation Occur Readily in ES Cells Doubly-Deficient for MacroH2A1 and MacroH2A2

Macrohistones (mH2As) are unusual histone variants found exclusively in vertebrate chromatin. In mice, the H2afy gene encodes two splice variants, mH2A1.1 and mH2A1.2 and a second gene, H2afy2, encodes an additional mH2A2 protein. Both mH2A isoforms have been found enriched on the inactive X chromos...

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Detalles Bibliográficos
Autores principales: Tanasijevic, Borko, Rasmussen, Theodore P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127949/
https://www.ncbi.nlm.nih.gov/pubmed/21738686
http://dx.doi.org/10.1371/journal.pone.0021512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127949/
https://www.ncbi.nlm.nih.gov/pubmed/21738686
http://dx.doi.org/10.1371/journal.pone.0021512

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