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The CDK9/Cyclin T1 subunits of P-TEFb in mouse oocytes and preimplantation embryos: A possible role in embryonic genome activation

BACKGROUND: Two stages of genome activation have been identified in the mouse embryo. Specifically, minor transcriptional activation is evident at the one-cell stage and a second major episode of activation occurs at the two-cell stage. Nuclear translocation of RNA polymerase II and phosphorylation...

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Detalles Bibliográficos
Autores principales: Oqani, Reza K, Kim, Hong R, Diao, Yun F, Park, Chang S, Jin, Dong I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127986/
https://www.ncbi.nlm.nih.gov/pubmed/21639898
http://dx.doi.org/10.1186/1471-213X-11-33