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HAPIscreen, a method for high-throughput aptamer identification

BACKGROUND: Aptamers are oligonucleotides displaying specific binding properties for a predetermined target. They are selected from libraries of randomly synthesized candidates through an in vitro selection process termed SELEX (Systematic Evolution of Ligands by EXponential enrichment) alternating...

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Detalles Bibliográficos
Autores principales: Dausse, Eric, Taouji, Saïd, Evadé, Laetitia, Di Primo, Carmelo, Chevet, Eric, Toulmé, Jean-Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127992/
https://www.ncbi.nlm.nih.gov/pubmed/21639912
http://dx.doi.org/10.1186/1477-3155-9-25