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NFκB1 and NFκBIA Polymorphisms Are Associated with Increased Risk for Sporadic Colorectal Cancer in a Southern Chinese Population

BACKGROUND: Nuclear factor κB (NFκB) plays a key role in the regulation of apoptosis. The function of NFκB is inhibited by binding to NFκB inhibitor (IκB), and disruption of the balance of NFκB and IκB is related to the development of many diseases, including tumors. Therefore, we hypothesized that...

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Detalles Bibliográficos
Autores principales: Song, Shunxin, Chen, Dianke, Lu, Jiachun, Liao, Jiawei, Luo, Yanxin, Yang, Zuli, Fu, Xinhui, Fan, Xinjuan, Wei, Yisheng, Yang, Lei, Wang, Lei, Wang, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128094/
https://www.ncbi.nlm.nih.gov/pubmed/21738780
http://dx.doi.org/10.1371/journal.pone.0021726