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Genome-Wide Association Study of White Blood Cell Count in 16,388 African Americans: the Continental Origins and Genetic Epidemiology Network (COGENT)

Total white blood cell (WBC) and neutrophil counts are lower among individuals of African descent due to the common African-derived “null” variant of the Duffy Antigen Receptor for Chemokines (DARC) gene. Additional common genetic polymorphisms were recently associated with total WBC and WBC sub-typ...

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Detalles Bibliográficos
Autores principales: Reiner, Alexander P., Lettre, Guillaume, Nalls, Michael A., Ganesh, Santhi K., Mathias, Rasika, Austin, Melissa A., Dean, Eric, Arepalli, Sampath, Britton, Angela, Chen, Zhao, Couper, David, Curb, J. David, Eaton, Charles B., Fornage, Myriam, Grant, Struan F. A., Harris, Tamara B., Hernandez, Dena, Kamatini, Naoyuki, Keating, Brendan J., Kubo, Michiaki, LaCroix, Andrea, Lange, Leslie A., Liu, Simin, Lohman, Kurt, Meng, Yan, Mohler, Emile R., Musani, Solomon, Nakamura, Yusuke, O'Donnell, Christopher J., Okada, Yukinori, Palmer, Cameron D., Papanicolaou, George J., Patel, Kushang V., Singleton, Andrew B., Takahashi, Atsushi, Tang, Hua, Taylor, Herman A., Taylor, Kent, Thomson, Cynthia, Yanek, Lisa R., Yang, Lingyao, Ziv, Elad, Zonderman, Alan B., Folsom, Aaron R., Evans, Michele K., Liu, Yongmei, Becker, Diane M., Snively, Beverly M., Wilson, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128101/
https://www.ncbi.nlm.nih.gov/pubmed/21738479
http://dx.doi.org/10.1371/journal.pgen.1002108