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Genome-Wide Association of Bipolar Disorder Suggests an Enrichment of Replicable Associations in Regions near Genes

Although a highly heritable and disabling disease, bipolar disorder's (BD) genetic variants have been challenging to identify. We present new genotype data for 1,190 cases and 401 controls and perform a genome-wide association study including additional samples for a total of 2,191 cases and 1,...

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Detalles Bibliográficos
Autores principales: Smith, Erin N., Koller, Daniel L., Panganiban, Corrie, Szelinger, Szabolcs, Zhang, Peng, Badner, Judith A., Barrett, Thomas B., Berrettini, Wade H., Bloss, Cinnamon S., Byerley, William, Coryell, William, Edenberg, Howard J., Foroud, Tatiana, Gershon, Elliot S., Greenwood, Tiffany A., Guo, Yiran, Hipolito, Maria, Keating, Brendan J., Lawson, William B., Liu, Chunyu, Mahon, Pamela B., McInnis, Melvin G., McMahon, Francis J., McKinney, Rebecca, Murray, Sarah S., Nievergelt, Caroline M., Nurnberger, John I., Nwulia, Evaristus A., Potash, James B., Rice, John, Schulze, Thomas G., Scheftner, William A., Shilling, Paul D., Zandi, Peter P., Zöllner, Sebastian, Craig, David W., Schork, Nicholas J., Kelsoe, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128104/
https://www.ncbi.nlm.nih.gov/pubmed/21738484
http://dx.doi.org/10.1371/journal.pgen.1002134