Cryptic Transcription Mediates Repression of Subtelomeric Metal Homeostasis Genes

Nonsense-mediated mRNA decay (NMD) prevents the accumulation of transcripts bearing premature termination codons. Here we show that Saccharomyces cerevisiae NMD mutants accumulate 5′–extended RNAs (CD-CUTs) of many subtelomeric genes. Using the subtelomeric ZRT1 and FIT3 genes activated in response...

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Detalles Bibliográficos
Autores principales: Toesca, Isabelle, Nery, Camille R., Fernandez, Cesar F., Sayani, Shakir, Chanfreau, Guillaume F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128112/
https://www.ncbi.nlm.nih.gov/pubmed/21738494
http://dx.doi.org/10.1371/journal.pgen.1002163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128112/
https://www.ncbi.nlm.nih.gov/pubmed/21738494
http://dx.doi.org/10.1371/journal.pgen.1002163

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