HIV-1 Efficient Entry in Inner Foreskin Is Mediated by Elevated CCL5/RANTES that Recruits T Cells and Fuels Conjugate Formation with Langerhans Cells

Male circumcision reduces acquisition of HIV-1 by 60%. Hence, the foreskin is an HIV-1 entry portal during sexual transmission. We recently reported that efficient HIV-1 transmission occurs following 1 h of polarized exposure of the inner, but not outer, foreskin to HIV-1-infected cells, but not to...

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Detalles Bibliográficos
Autores principales: Zhou, Zhicheng, Barry de Longchamps, Nicolas, Schmitt, Alain, Zerbib, Marc, Vacher-Lavenu, Marie-Cécile, Bomsel, Morgane, Ganor, Yonatan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128116/
https://www.ncbi.nlm.nih.gov/pubmed/21738469
http://dx.doi.org/10.1371/journal.ppat.1002100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128116/
https://www.ncbi.nlm.nih.gov/pubmed/21738469
http://dx.doi.org/10.1371/journal.ppat.1002100

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