Distinguishing benign from malignant parotid gland tumours: low-dose multi-phasic CT protocol with 5-minute delay

OBJECTIVES: To explore the percentage enhancement wash-out ratio (PEW) and relative PEW (RPEW) of low-dose multi-phasic computed tomography (CT) in distinguishing benign from malignant parotid gland tumours. METHODS: This study was approved by the ethics committee, and informed patient consent was o...

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Autores principales: Jin, G. Q., Su, D. K., Xie, D., Zhao, W., Liu, L. D., Zhu, X. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128264/
https://www.ncbi.nlm.nih.gov/pubmed/21547526
http://dx.doi.org/10.1007/s00330-011-2101-y
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author Jin, G. Q.
Su, D. K.
Xie, D.
Zhao, W.
Liu, L. D.
Zhu, X. N.
author_facet Jin, G. Q.
Su, D. K.
Xie, D.
Zhao, W.
Liu, L. D.
Zhu, X. N.
author_sort Jin, G. Q.
collection PubMed
description OBJECTIVES: To explore the percentage enhancement wash-out ratio (PEW) and relative PEW (RPEW) of low-dose multi-phasic computed tomography (CT) in distinguishing benign from malignant parotid gland tumours. METHODS: This study was approved by the ethics committee, and informed patient consent was obtained. 51 patients with parotid tumours proven by histopathology received CT, including 18 with pleomorphic adenomas, 14 with Warthin’s tumours and 19 with malignant tumours. Size and attenuation of parotid tumours were measured. Compared with 5-min attenuation, the 30-s and 90-s PEW (PEW(30,) PEW(90)) and RPEW (RPEW(30), RPEW(90)) were calculated. RESULTS: There was a significant difference in PEW(30), RPEW(30), PEW(90) and RPEW(90) in the parotid neoplasms groups (P < 0.01), and statistical significance existed simultaneously in pleomorphic adenomas vs malignant tumours and Warthin’s tumours vs malignant tumours according to SNK-q test. The optimal diagnosis results of malignancy with 100% specificity (32/32) was obtained by using a combination of the following criteria: −70% > PEW(30) < 36%, −30% > PEW(30) < 19%, PEW(90) > 12%, and the sensitivity (74%) for diagnosis of malignancy was yield. CONCLUSIONS: Wash-out ratio may assist in differentiating the benign from malignant parotid gland tumours. Combining the percentage of enhanced wash-out ratios of CT protocols can yield diagnostic results for malignancy.
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spelling pubmed-31282642011-08-10 Distinguishing benign from malignant parotid gland tumours: low-dose multi-phasic CT protocol with 5-minute delay Jin, G. Q. Su, D. K. Xie, D. Zhao, W. Liu, L. D. Zhu, X. N. Eur Radiol Head and Neck OBJECTIVES: To explore the percentage enhancement wash-out ratio (PEW) and relative PEW (RPEW) of low-dose multi-phasic computed tomography (CT) in distinguishing benign from malignant parotid gland tumours. METHODS: This study was approved by the ethics committee, and informed patient consent was obtained. 51 patients with parotid tumours proven by histopathology received CT, including 18 with pleomorphic adenomas, 14 with Warthin’s tumours and 19 with malignant tumours. Size and attenuation of parotid tumours were measured. Compared with 5-min attenuation, the 30-s and 90-s PEW (PEW(30,) PEW(90)) and RPEW (RPEW(30), RPEW(90)) were calculated. RESULTS: There was a significant difference in PEW(30), RPEW(30), PEW(90) and RPEW(90) in the parotid neoplasms groups (P < 0.01), and statistical significance existed simultaneously in pleomorphic adenomas vs malignant tumours and Warthin’s tumours vs malignant tumours according to SNK-q test. The optimal diagnosis results of malignancy with 100% specificity (32/32) was obtained by using a combination of the following criteria: −70% > PEW(30) < 36%, −30% > PEW(30) < 19%, PEW(90) > 12%, and the sensitivity (74%) for diagnosis of malignancy was yield. CONCLUSIONS: Wash-out ratio may assist in differentiating the benign from malignant parotid gland tumours. Combining the percentage of enhanced wash-out ratios of CT protocols can yield diagnostic results for malignancy. Springer-Verlag 2011-03-11 2011 /pmc/articles/PMC3128264/ /pubmed/21547526 http://dx.doi.org/10.1007/s00330-011-2101-y Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Head and Neck
Jin, G. Q.
Su, D. K.
Xie, D.
Zhao, W.
Liu, L. D.
Zhu, X. N.
Distinguishing benign from malignant parotid gland tumours: low-dose multi-phasic CT protocol with 5-minute delay
title Distinguishing benign from malignant parotid gland tumours: low-dose multi-phasic CT protocol with 5-minute delay
title_full Distinguishing benign from malignant parotid gland tumours: low-dose multi-phasic CT protocol with 5-minute delay
title_fullStr Distinguishing benign from malignant parotid gland tumours: low-dose multi-phasic CT protocol with 5-minute delay
title_full_unstemmed Distinguishing benign from malignant parotid gland tumours: low-dose multi-phasic CT protocol with 5-minute delay
title_short Distinguishing benign from malignant parotid gland tumours: low-dose multi-phasic CT protocol with 5-minute delay
title_sort distinguishing benign from malignant parotid gland tumours: low-dose multi-phasic ct protocol with 5-minute delay
topic Head and Neck
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128264/
https://www.ncbi.nlm.nih.gov/pubmed/21547526
http://dx.doi.org/10.1007/s00330-011-2101-y
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