The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans

Despite the importance of microRNAs (miRNAs) in gene regulation, it is unclear how the miRNA–Argonaute complex—or miRNA-induced silencing complex (miRISC)—can regulate the translation of their targets in such diverse ways. We demonstrate here a direct interaction between the miRISC and the ribosome...

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Detalles Bibliográficos
Autores principales: Jannot, Guillaume, Bajan, Sarah, Giguère, Nellie J, Bouasker, Samir, Banville, Isabelle H, Piquet, Sandra, Hutvagner, Gyorgy, Simard, Martin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Scientific Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128278/
https://www.ncbi.nlm.nih.gov/pubmed/21525958
http://dx.doi.org/10.1038/embor.2011.66

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128278/
https://www.ncbi.nlm.nih.gov/pubmed/21525958
http://dx.doi.org/10.1038/embor.2011.66

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