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The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans
Despite the importance of microRNAs (miRNAs) in gene regulation, it is unclear how the miRNA–Argonaute complex—or miRNA-induced silencing complex (miRISC)—can regulate the translation of their targets in such diverse ways. We demonstrate here a direct interaction between the miRISC and the ribosome...
Autores principales: | Jannot, Guillaume, Bajan, Sarah, Giguère, Nellie J, Bouasker, Samir, Banville, Isabelle H, Piquet, Sandra, Hutvagner, Gyorgy, Simard, Martin J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128278/ https://www.ncbi.nlm.nih.gov/pubmed/21525958 http://dx.doi.org/10.1038/embor.2011.66 |
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