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Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence

OBJECTIVE: Uncovering the dominant molecular deregulation among the multitude of pathways implicated in aggressive prostate cancer is essential to intelligently developing targeted therapies. Paradoxically, published prostate cancer gene expression signatures of poor prognosis share little overlap a...

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Detalles Bibliográficos
Autores principales: Chen, James L, Li, Jianrong, Stadler, Walter M, Lussier, Yves A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128407/
https://www.ncbi.nlm.nih.gov/pubmed/21672909
http://dx.doi.org/10.1136/amiajnl-2011-000178