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Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization

Most mitochondrial proteins are encoded in the nucleus as precursor proteins and carry N-terminal presequences for import into the organelle. The vast majority of presequences are proteolytically removed by the mitochondrial processing peptidase (MPP) localized in the matrix. A subset of precursors...

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Detalles Bibliográficos
Autores principales: Vögtle, F.-Nora, Prinz, Claudia, Kellermann, Josef, Lottspeich, Friedrich, Pfanner, Nikolaus, Meisinger, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128517/
https://www.ncbi.nlm.nih.gov/pubmed/21525245
http://dx.doi.org/10.1091/mbc.E11-02-0169