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Glioblastoma motility occurs in the absence of actin polymer

In fibroblasts and keratocytes, motility is actin dependent, while microtubules play a secondary role, providing directional guidance. We demonstrate here that the motility of glioblastoma cells is exceptional, in that it occurs in cells depleted of assembled actin. Cells display persistent motility...

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Detalles Bibliográficos
Autores principales: Panopoulos, Andreas, Howell, Michael, Fotedar, Rati, Margolis, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128524/
https://www.ncbi.nlm.nih.gov/pubmed/21551075
http://dx.doi.org/10.1091/mbc.E10-10-0849