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Signal sequence–independent SRP-SR complex formation at the membrane suggests an alternative targeting pathway within the SRP cycle

Protein targeting by the signal recognition particle (SRP) and the bacterial SRP receptor FtsY requires a series of closely coordinated steps that monitor the presence of a substrate, the membrane, and a vacant translocon. Although the influence of substrate binding on FtsY-SRP complex formation is...

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Detalles Bibliográficos
Autores principales: Braig, David, Mircheva, Miryana, Sachelaru, Ilie, van der Sluis, Eli O., Sturm, Lukas, Beckmann, Roland, Koch, Hans-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128533/
https://www.ncbi.nlm.nih.gov/pubmed/21551068
http://dx.doi.org/10.1091/mbc.E11-02-0152