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Release mode of large and small dense-core vesicles specified by different synaptotagmin isoforms in PC12 cells

Many cells release multiple substances in different proportions according to the specific character of a stimulus. PC12 cells, a model neuroendocrine cell line, express multiple isoforms of the exocytotic Ca(2+) sensor synaptotagmin. We show that these isoforms sort to populations of dense-core vesi...

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Detalles Bibliográficos
Autores principales: Zhang, Zhen, Wu, Yao, Wang, Zhao, Dunning, F. Mark, Rehfuss, Jonathan, Ramanan, Deepshika, Chapman, Edwin R., Jackson, Meyer B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128534/
https://www.ncbi.nlm.nih.gov/pubmed/21551071
http://dx.doi.org/10.1091/mbc.E11-02-0159