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Dysregulated Arl1, a regulator of post-Golgi vesicle tethering, can inhibit endosomal transport and cell proliferation in yeast

Small monomeric G proteins regulated in part by GTPase-activating proteins (GAPs) are molecular switches for several aspects of vesicular transport. The yeast Gcs1 protein is a dual-specificity GAP for ADP-ribosylation factor (Arf) and Arf-like (Arl)1 G proteins, and also has GAP-independent activit...

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Detalles Bibliográficos
Autores principales: Benjamin, Jeremy J. R., Poon, Pak P., Drysdale, John D., Wang, Xiangmin, Singer, Richard A., Johnston, Gerald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128535/
https://www.ncbi.nlm.nih.gov/pubmed/21562219
http://dx.doi.org/10.1091/mbc.E10-09-0765