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Sequential assembly of translesion DNA polymerases at UV-induced DNA damage sites

In response to DNA damage such as from UV irradiation, mammalian Y-family translesion synthesis (TLS) polymerases Polη and Rev1 colocalize with proliferating cell nuclear antigen at nuclear foci, presumably representing stalled replication sites. However, it is unclear whether the localization of on...

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Detalles Bibliográficos
Autores principales: Andersen, Parker L., Xu, Fang, Ziola, Barry, McGregor, W. Glen, Xiao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128538/
https://www.ncbi.nlm.nih.gov/pubmed/21551069
http://dx.doi.org/10.1091/mbc.E10-12-0938