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Mms1 and Mms22 stabilize the replisome during replication stress

Mms1 and Mms22 form a Cul4(Ddb1)-like E3 ubiquitin ligase with the cullin Rtt101. In this complex, Rtt101 is bound to the substrate-specific adaptor Mms22 through a linker protein, Mms1. Although the Rtt101(Mms1/Mms22) ubiquitin ligase is important in promoting replication through damaged templates,...

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Detalles Bibliográficos
Autores principales: Vaisica, Jessica A., Baryshnikova, Anastasija, Costanzo, Michael, Boone, Charles, Brown, Grant W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128540/
https://www.ncbi.nlm.nih.gov/pubmed/21593207
http://dx.doi.org/10.1091/mbc.E10-10-0848