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Cutaneous Squamous Cell Carcinoma (SCC) and the DNA Damage Response: pATM Expression Patterns in Pre-Malignant and Malignant Keratinocyte Skin Lesions

Recent evidence suggests that an initial barrier to the emergence of tumours is a DNA damage response that evokes a counter-response which arrests the growth of, or eliminates, damaged cells. Early precursor lesions express markers of an activated DNA damage response in several types of tumour, with...

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Detalles Bibliográficos
Autores principales: Ismail, Ferina, Ikram, Mohamed, Purdie, Karin, Harwood, Catherine, Leigh, Irene, Storey, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128585/
https://www.ncbi.nlm.nih.gov/pubmed/21747934
http://dx.doi.org/10.1371/journal.pone.0021271