NRF2 Activation Restores Disease Related Metabolic Deficiencies in Olfactory Neurosphere-Derived Cells from Patients with Sporadic Parkinson's Disease

BACKGROUND: Without appropriate cellular models the etiology of idiopathic Parkinson's disease remains unknown. We recently reported a novel patient-derived cellular model generated from biopsies of the olfactory mucosa (termed olfactory neurosphere-derived (hONS) cells) which express functiona...

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Detalles Bibliográficos
Autores principales: Cook, Anthony L., Vitale, Alejandra M., Ravishankar, Sugandha, Matigian, Nicholas, Sutherland, Greg T., Shan, Jiangou, Sutharsan, Ratneswary, Perry, Chris, Silburn, Peter A., Mellick, George D., Whitelaw, Murray L., Wells, Christine A., Mackay-Sim, Alan, Wood, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128624/
https://www.ncbi.nlm.nih.gov/pubmed/21747966
http://dx.doi.org/10.1371/journal.pone.0021907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128624/
https://www.ncbi.nlm.nih.gov/pubmed/21747966
http://dx.doi.org/10.1371/journal.pone.0021907

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