Electrostatic Modifications of the Human Leukocyte Antigen-DR P9 Peptide-Binding Pocket and Susceptibility to Primary Sclerosing Cholangitis

The strongest genetic risk factors for primary sclerosing cholangitis (PSC) are found in the human leukocyte antigen (HLA) complex at chromosome 6p21. Genes in the HLA class II region encode molecules that present antigen to T lymphocytes. Polymorphisms in these genes are associated with most autoim...

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Detalles Bibliográficos
Autores principales: Hov, Johannes R, Kosmoliaptsis, Vasilis, Traherne, James A, Olsson, Marita, Boberg, Kirsten M, Bergquist, Annika, Schrumpf, Erik, Bradley, J Andrew, Taylor, Craig J, Lie, Benedicte A, Trowsdale, John, Karlsen, Tom H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Autoimmune, Cholestatic and Biliary Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128712/
https://www.ncbi.nlm.nih.gov/pubmed/21413052
http://dx.doi.org/10.1002/hep.24299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128712/
https://www.ncbi.nlm.nih.gov/pubmed/21413052
http://dx.doi.org/10.1002/hep.24299

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