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CD28 and IL-4: two heavyweights controlling the balance between immunity and inflammation

The costimulatory receptor CD28 and IL-4Rα-containing cytokine receptors play key roles in controlling the size and quality of pathogen-specific immune responses. Thus, CD28-mediated costimulation is needed for effective primary T-cell expansion and for the generation and activation of regulatory T-...

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Detalles Bibliográficos
Autores principales: Hünig, Thomas, Lühder, Fred, Elflein, Karin, Gogishvili, Tea, Fröhlich, Monika, Guler, Reto, Cutler, Antony, Brombacher, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128750/
https://www.ncbi.nlm.nih.gov/pubmed/20390297
http://dx.doi.org/10.1007/s00430-010-0156-z