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CD28 and IL-4: two heavyweights controlling the balance between immunity and inflammation
The costimulatory receptor CD28 and IL-4Rα-containing cytokine receptors play key roles in controlling the size and quality of pathogen-specific immune responses. Thus, CD28-mediated costimulation is needed for effective primary T-cell expansion and for the generation and activation of regulatory T-...
Autores principales: | Hünig, Thomas, Lühder, Fred, Elflein, Karin, Gogishvili, Tea, Fröhlich, Monika, Guler, Reto, Cutler, Antony, Brombacher, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128750/ https://www.ncbi.nlm.nih.gov/pubmed/20390297 http://dx.doi.org/10.1007/s00430-010-0156-z |
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