Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in breast cancer

BACKGROUND: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biological pathways of regulation. Most current approaches either depend on linear correlation or on nonparametric tests of asso...

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Detalles Bibliográficos
Autores principales: Solvang, Hiroko K, Lingjærde, Ole Christian, Frigessi, Arnoldo, Børresen-Dale, Anne-Lise, Kristensen, Vessela N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128865/
https://www.ncbi.nlm.nih.gov/pubmed/21609452
http://dx.doi.org/10.1186/1471-2105-12-197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128865/
https://www.ncbi.nlm.nih.gov/pubmed/21609452
http://dx.doi.org/10.1186/1471-2105-12-197

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