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Prognostic significance of the FLT3 ITD mutation in patients with normal-karyotype acute myeloid leukemia in relapse

BACKGROUND: Fms-like tyrosine kinase 3 internal tandem duplication (FLT3 ITD) mutation is related to poor prognosis in normal-karyotype acute myeloid leukemia (AML). However, the prognostic significance of the mutation at relapse has not been adequately investigated. We investigated the prognostic s...

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Detalles Bibliográficos
Autores principales: Park, Sang Hyuk, Chi, Hyun-Sook, Min, Sook-Kyung, Cho, Young-Uk, Jang, Seongsoo, Park, Chan-Jeoung, Lee, Jung-Hee, Lee, Je-Hwan, Lee, Kyoo-Hyung, Im, Ho-Joon, Seo, Jong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128906/
https://www.ncbi.nlm.nih.gov/pubmed/21747880
http://dx.doi.org/10.5045/kjh.2011.46.2.88