A Workflow for Global Sensitivity Analysis of PBPK Models

Physiologically based pharmacokinetic (PBPK) models have a potentially significant role in the development of a reliable predictive toxicity testing strategy. The structure of PBPK models are ideal frameworks into which disparate in vitro and in vivo data can be integrated and utilized to translate...

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Detalles Bibliográficos
Autores principales: McNally, Kevin, Cotton, Richard, Loizou, George D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128931/
https://www.ncbi.nlm.nih.gov/pubmed/21772819
http://dx.doi.org/10.3389/fphar.2011.00031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128931/
https://www.ncbi.nlm.nih.gov/pubmed/21772819
http://dx.doi.org/10.3389/fphar.2011.00031

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