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A Workflow for Global Sensitivity Analysis of PBPK Models

Physiologically based pharmacokinetic (PBPK) models have a potentially significant role in the development of a reliable predictive toxicity testing strategy. The structure of PBPK models are ideal frameworks into which disparate in vitro and in vivo data can be integrated and utilized to translate...

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Detalles Bibliográficos
Autores principales:	McNally, Kevin, Cotton, Richard, Loizou, George D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2011
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128931/ https://www.ncbi.nlm.nih.gov/pubmed/21772819 http://dx.doi.org/10.3389/fphar.2011.00031

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