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Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation

BACKGROUND: Kainic acid (KA)-induced status epilepticus (SE) was involved with release of free radicals. Sesamin is a well-known antioxidant from sesame seeds and it scavenges free radicals in several brain injury models. However the neuroprotective mechanism of sesamin to KA-induced seizure has not...

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Detalles Bibliográficos
Autores principales: Hsieh, Peiyuan F, Hou, Chien-Wei, Yao, Pei-Wun, Wu, Szu-Pei, Peng, Yu-Fen, Shen, Mei-Lin, Lin, Ching-Huei, Chao, Ya-Yun, Chang, Ming-Hong, Jeng, Kee-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129306/
https://www.ncbi.nlm.nih.gov/pubmed/21609430
http://dx.doi.org/10.1186/1742-2094-8-57