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Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells

BACKGROUND: Astrocytomas are the most common and aggressive brain tumors characterized by their highly invasive growth. Gain of chromosome 7 with a hot spot at 7q32 appears to be the most prominent aberration in astrocytoma. Previously reports have shown that microRNA-335 (miR-335) resided on chromo...

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Detalles Bibliográficos
Autores principales: Shu, Minfeng, Zheng, Xiaoke, Wu, Sihan, Lu, Huimin, Leng, Tiandong, Zhu, Wenbo, Zhou, Yuehan, Ou, Yanqiu, Lin, Xi, Lin, Yuan, Xu, Dong, Zhou, Yuxi, Yan, Guangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129318/
https://www.ncbi.nlm.nih.gov/pubmed/21592405
http://dx.doi.org/10.1186/1476-4598-10-59