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A graphical method for practical and informative identifiability analyses of physiological models: A case study of insulin kinetics and sensitivity

BACKGROUND: Derivative based a-priori structural identifiability analyses of mathematical models can offer valuable insight into the identifiability of model parameters. However, these analyses are only capable of a binary confirmation of the mathematical distinction of parameters and a positive out...

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Detalles Bibliográficos
Autores principales: Docherty, Paul D, Chase, J Geoffrey, Lotz, Thomas F, Desaive, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129319/
https://www.ncbi.nlm.nih.gov/pubmed/21615928
http://dx.doi.org/10.1186/1475-925X-10-39